CodeGeneratorNeosurf
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8/06/2020 19:17:40
A verification code is sent to your mobile. You can then redeem a free gift card from your mobile. Details are available at the banner on the left.Microalbuminuria predicts new onset of type 2 diabetes mellitus during a two-year follow-up of hypertensive patients without diabetes.
The aim of the present study was to evaluate the predictive ability of urinary albumin and lipid excretions for the development of type 2 diabetes mellitus in hypertensive patients without overt diabetes. A total of 232 hypertensive patients without overt diabetes were followed up for 2 years. Out of the 232 patients, 73 (31.5%) were men and 159 (68.5%) were women. During the follow-up period, 26 (11.2%) patients developed new onset of diabetes. Microalbuminuria was defined as albumin excretion >or=20 microg/min. We compared patients who developed diabetes with those who did not develop diabetes. The mean age was 64.5 years and the mean duration of hypertension was 10.8 +/- 5.1 years. During the follow-up period, 22 patients (9.4%) developed new onset of diabetes. Microalbuminuria was more frequent in patients who developed diabetes compared to those who did not develop diabetes (52.4% vs. 26.8%, P = 0.007). The multivariate logistic regression analysis showed microalbuminuria (P = 0.016) and metabolic syndrome (P = 0.008) to be independent predictors of the development of diabetes. Microalbuminuria also predicted diabetes development with a sensitivity of 63.6% and a specificity of 66.4%. In conclusion, we demonstrated that microalbuminuria predicted the new onset of type 2 diabetes mellitus in hypertensive patients without overt diabetes.Partnerships
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